化工社化工社 化学情報印刷レポート · 研究参考用
Water → [5-((E)-1,5-diethyl-5-triethylsilanyloxyhept-1-enyl)-3-thienyl]methanol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Sodium borohydride | HCID 4311764 | — |
| 反応物 | 5-((E)-1,5-diethyl-5-triethylsilanyloxyhept-1-enyl)thiophene-3-carbaldehyde | HCID 86759389 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | [5-((E)-1,5-diethyl-5-triethylsilanyloxyhept-1-enyl)-3-thienyl]methanol | HCID 69825153 | — |
反応手順
4 g (9.9 mmol) of 5-((E)-1,5-diethyl-5-triethylsilanyloxyhept-1-enyl)thiophene-3-carbaldehyde are dissolved in 50 mL of THF and 50 mL of methanol. 1 g (26 mmol) of sodium borohydride is then added portionwise. The reaction medium is stirred for 1 hour and then poured into 100 mL of water. After purification by chromatography on silica gel, the desired product is obtained in the form of a colourless oil (m=4 g; Y=100%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06706725B1 |
| 出典データセット | uspto-grants-2004_03 |
| ORD ID | ord-9205c61af32d4e83aed778fc45781fe5 |
| 出典メモ | uspto-grants-2004_03 |