2-(2-Ethyl-[1,3]dioxolan-2-yl)thiophene-4-carbaldehyde → Dimethyl 4-{(e)-2-[2-(2-ethyl-[1,3]dioxolan-2-yl)-4-thienyl]vinyl}phthalate

Participants

Reaction Steps

In a manner similar to that of Example 8(a), by reaction of 4.6 g (21.6 mmol) of 2-(2-ethyl-[1,3]dioxolan-2-yl)thiophene-4-carbaldehyde with 8.9 g (26 mmol) of dimethyl 4-(diethoxyphosphorylmethyl)-phthalate and 2.9 g (26 mmol) of potassium tert-butoxide, the desired product is obtained in the form of a yellow oil (m=7 g; Y=87%).

Provenance & Evidence