3-Hydroxy-5-chloropyridine → Methyl 5-chloro-2-{[(5-chloropyridin-3-yl)oxy]methyl}benzoate

HRID 493549Notes

Reaction equation

HRID 493549 reaction equation
Br[CH2:2][C:3]1[CH:12]=[CH:11][C:10]([Cl:13])=[CH:9][C:4]=1[C:5]([O:7][CH3:8])=[O:6].[Cl:14][C:15]1[CH:16]=[N:17][CH:18]=[C:19]([OH:21])[CH:20]=1>>[Cl:13][C:10]1[CH:11]=[CH:12][C:3]([CH2:2][O:21][C:19]2[CH:18]=[N:17][CH:16]=[C:15]([Cl:14])[CH:20]=2)=[C:4]([CH:9]=1)[C:5]([O:7][CH3:8])=[O:6]

Participants

3

Reactant 2

HCID 5823053-Hydroxy-5-chloropyridineHCID 51358462Methyl 2-(bromomethyl)-5-chlorobenzoate

Product 1

HCID 68861963Methyl 5-chloro-2-{[(5-chloropyridin-3-yl)oxy]methyl}benzoate

Procedure

The title compound was prepared according to the procedure described in step 1 of Example 1 from methyl 2-(bromomethyl)-5-chlorobenzoate and 3-chloro-5-hydroxypyridine:

Sources & evidence

ORD record
ord-18743a9a1d614ad98b13f3d6eac78434
Source dataset
uspto-grants-2009_05
Patent number
US07534914B2

Reaction notes

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