1{5-[3,4-Bis(tert-butyldimethylsilanyloxymethyl)phenoxymethyl]-3-thienyl}-1-propanol → HCID 20636288, compound

HRID 49360Notes

Reaction equation

HRID 49360 reaction equation
[Si:1]([O:8][CH2:9][C:10]1[CH:11]=[C:12]([CH:24]=[CH:25][C:26]=1[CH2:27][O:28][Si:29]([C:32]([CH3:35])([CH3:34])[CH3:33])([CH3:31])[CH3:30])[O:13][CH2:14][C:15]1[S:19][CH:18]=[C:17]([CH:20]([OH:23])[CH2:21][CH3:22])[CH:16]=1)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2]>[O-2].[O-2].[Mn+4]>[Si:1]([O:8][CH2:9][C:10]1[CH:11]=[C:12]([CH:24]=[CH:25][C:26]=1[CH2:27][O:28][Si:29]([C:32]([CH3:33])([CH3:35])[CH3:34])([CH3:30])[CH3:31])[O:13][CH2:14][C:15]1[S:19][CH:18]=[C:17]([C:20](=[O:23])[CH2:21][CH3:22])[CH:16]=1)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2]

Participants

3

Reactant 1

HCID 698246201{5-[3,4-Bis(tert-butyldimethylsilanyloxymethyl)phenoxymethyl]-3-thienyl}-1-propanol

Product 1

HCID 20636288HCID 20636288, compound

Reagents, catalysts & solvents 1

HCID 178418406HCID 178418406, compoundCatalyst

Procedure

In a manner similar to that of Example 9(b), by reaction of 28 g (52 mmol) of 1{5-[3,4-bis(tert-butyldimethylsilanyloxymethyl)phenoxymethyl]-3-thienyl}-1-propanol with 45 g (520 mmol) of manganese dioxide, the desired product is obtained in the form of an orange-coloured oil (m=26 g; Y=93%).

Sources & evidence

ORD record
ord-2618e92ed6874584b627f64ca56fb515
Source dataset
uspto-grants-2004_03
Patent number
US06706725B1

Reaction notes

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