Sodium Carbonate → HCID 15288220, compound

HRID 4937Notes

Reaction equation

HRID 4937 reaction equation
[CH3:1][N:2]1[CH2:6][C:5]2[CH:7]=[CH:8][C:9]3[C:13](=[O:14])[C:12](=[O:15])[NH:11][C:10]=3[C:4]=2[CH2:3]1.[Br:16]Br.C([O-])([O-])=O.[Na+].[Na+]>O.C(O)C>[Br:16][C:7]1[C:5]2[CH2:6][N:2]([CH3:1])[CH2:3][C:4]=2[C:10]2[NH:11][C:12](=[O:15])[C:13](=[O:14])[C:9]=2[CH:8]=1

Participants

6

Reactant 3

HCID 10340Sodium CarbonateHCID 24408BromineHCID 19919665HCID 19919665, compound

Product 1

HCID 15288220HCID 15288220, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 962WaterSolvent

Procedure

To a stirred suspension of 1,6,7,8-tetrahydro-7-methylbenzo[2,1-b:3,4-c']dipyrrole-2,3-dione (0.5 g, 2.48 mmol) in water (20 ml) was added a solution of bromine (0.7 ml) in ethanol (5 ml). After 5 hours stirring at room temperature the reaction was completed and pH was adjusted to 8 with sat Na2CO3. The precipitated product was filtered off and washed with water, M.p. >300° C.

Workup

  1. filtrationThe precipitated product was filtered off
  2. washwashed with water, M.p. >300° C.

Sources & evidence

ORD record
ord-34ba7a5c0a8344839a71cd6270ce275f
Source dataset
uspto-grants-1993_09
Patent number
US05242918

Reaction notes

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