反应详情

To 10 ml of a methanol solution of a boron trifluoride methanol complex was added 0.25 g of methyl [2-(5-acetylamino-2-chloro-4-fluorophenoxy)phenoxy]acetate, and the mixture was heated and stirred for 3 hours. The reaction mixture was then concentrated. The residue was dissolved in ethyl acetate, and the solution was washed with saturated aqueous sodium bicarbonate solution, dried over magnesium sulfate, and then concentrated to give 0.2 g of methyl [2-(5-amino-2-chloro-4-fluorophenoxy)phenoxy]acetate.

1. temperaturethe mixture was heated
2. concentrationThe reaction mixture was then concentrated
3. dissolutionThe residue was dissolved in ethyl acetate
4. washthe solution was washed with saturated aqueous sodium bicarbonate solution
5. dry with materialdried over magnesium sulfate
6. concentrationconcentrated