Bromine → HCID 57682507, compound

HRID 493979Notes

Reaction equation

HRID 493979 reaction equation
[CH2:1]([C:3]1[C:4](=[O:14])[N:5]([CH3:13])[C:6]2[C:11]([N:12]=1)=[CH:10][CH:9]=[CH:8][CH:7]=2)[CH3:2].C([O-])(=O)C.[Na+].[Br:20]Br>CC(O)=O>[Br:20][CH:1]([C:3]1[C:4](=[O:14])[N:5]([CH3:13])[C:6]2[C:11]([N:12]=1)=[CH:10][CH:9]=[CH:8][CH:7]=2)[CH3:2]

Participants

5

Reactant 3

HCID 24408BromineHCID 517045Sodium AcetateHCID 604754HCID 604754, compound

Product 1

HCID 57682507HCID 57682507, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent2×

Procedure

To a mixture of a 3-ethyl-1-methyl-1H-quinoxalin-2-one (1 g) and anhydrous sodium acetate (0.523 g) in glacial AcOH (10 mL) was added dropwise over 10 min. a solution of bromine (0.273 mL) in glacial AcOH (6 mL). The resulting pale yellow suspension was stirred at rt under nitrogen for 2 h, cooled to 0° C., filtered and washed with cold-water to give the title compound as a pale yellow solid.

Workup

  1. temperaturecooled to 0° C.
  2. filtrationfiltered
  3. washwashed with cold-water

Sources & evidence

ORD record
ord-1b59d06a5e73431695df5da219de3e1a
Source dataset
uspto-grants-2009_05
Patent number
US07538109B2

Reaction notes

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