1-Methyl-4-piperidone → HCID 784206, compound

HRID 494017Notes

Reaction equation

HRID 494017 reaction equation
[CH3:1][N:2]1[CH2:7][CH2:6][C:5](=O)[CH2:4][CH2:3]1.[CH2:9]([N:16]1[CH2:21][CH2:20][CH:19]([NH:22][CH3:23])[CH2:18][CH2:17]1)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>>[CH3:23][N:22]([CH:19]1[CH2:18][CH2:17][N:16]([CH2:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[CH2:21][CH2:20]1)[CH:5]1[CH2:6][CH2:7][N:2]([CH3:1])[CH2:3][CH2:4]1

Participants

3

Reactant 2

HCID 740491-Methyl-4-piperidoneHCID 41361281-benzyl-N-methylpiperidin-4-amine

Product 1

HCID 784206HCID 784206, compoundYield 66%

Procedure

In operating analogously to preparation LXXI, starting with N-methyl-4-piperidinone and 1-benzyl-4-(methylamino)piperidine, the product sought after is obtained as a yellow oil (yield=66%).

Workup

  1. customIn operating analogously to preparation LXXI

Sources & evidence

ORD record
ord-5a5f66525303463ca6e2aa051e382a54
Source dataset
uspto-grants-2009_05
Patent number
US07538111B2

Reaction notes

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