Hydrochloric Acid → HCID 178486315, compound

Participants

Reaction Steps

A solution of Compound 16 (50 mg, 0.089 mmol) in Et2O (3 ml) was mixed through to a clear acidic reaction with ethereal HCl and with 4 drops of H2O. The mixture was subjected to ultrasound for one hour at room temperature and then evaporated. The residue (40 mg of white foam resin) was dissolved in H2O and freeze dried. Yield: 30 mg (79%) 17.2 HCl as white lyophilisate: 1H-NMR (CDCl3): δ 9.59 (s, OH—C(3)); 9.29 (s, br, NH+); 8.53 (d, J=8.0, C(6)-NH—); 7.29 (s, br, C(6)-NH—C(NH2)2+), 6.78 (d, J=8.1, 1 arom. H); 6.69 (d, J=8.1, 1 arom. H); 4.49 (d, J=7.2, H—C(5)); 3.26 (s, CH3O—C(14)); 2.84 (s, CH3N).

Provenance & Evidence