Hydrochloric Acid → HCID 178486316, compound

Participants

Reaction Steps

A solution of Compound 18 (50 mg, 0.089 mmol) in Et2O (3 ml) was mixed through to a clear acidic reaction with ethereal HCl and with 4 drops of H2O. The mixture was subjected to ultrasound for 1.5 h at room temperature and then evaporated. The residue (40 mg of white foam resin) was dissolved in H2O and freeze dried. Yield: 35 mg (92%) 19.2 HCl as white lyophilisate: 1H-NMR (CDCl3): δ 9.29 (s, br, NH+); 9.20 (s, OH—C(3)); 7.57 (d, J=8.8, C(6)-NH—); 7.46 (s, br, C(6)-NH—C(NH2)2+), 6.76 (d, J=8.1, 1 arom. H); 6.62 (d, J=8.1, 1 arom. H); 4.70 (d, J=4.0, H—C(5)); 3.36 (s, CH3O—C(14)); 2.88 (s, CH3N).

Provenance & Evidence