反应详情

Ethylamine (37 g, 0.82 mol) was condensed into a pressure vessel at 0° C. N-(tert-butoxycarbonyl)glycine methyl ester (50 mL, 0.34 mol) was added. The vessel was sealed and the mixture was stirred at room temperature overnight. The product mixture was concentrated under vacuum and the residue was passed through a pad of silica gel eluting with ethyl acetate. The solution was concentrated under vacuum to provide the title compound as a clear oil.

1. customcondensed into a pressure vessel at 0° C
2. customThe vessel was sealed
3. concentrationThe product mixture was concentrated under vacuum
4. concentrationThe solution was concentrated under vacuum