HRID494183

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID14798

Sodium Hydroxide

HNaO

HCID5092700

Ethyl 2-methyl-6-phenylpyridine-3-carboxylate

C15H15NO2

PRODUCTS

生成物

HCID822960

2-methyl-6-phenylnicotinic acid

C13H11NO2

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

Ethyl 2-methyl-6-phenylnicotinate (D18) (284 mg, 1.2 mmol) was treated with aq. 2M NaOH in ethanol at reflux giving the title compound as an off white solid (108 mg). MS (AP): MH+ 214, M-H+ 212.

WORKUP

后处理

temperatureat reflux