2,3-Dichloropyridine → 4-(3-Chloropyridin-2-yl)benzoic acid

HRID 494200Notes

Reaction equation

HRID 494200 reaction equation
[C:1]([C:4]1[CH:9]=[CH:8][C:7](B(O)O)=[CH:6][CH:5]=1)([OH:3])=[O:2].Cl[C:14]1[C:19]([Cl:20])=[CH:18][CH:17]=[CH:16][N:15]=1>>[Cl:20][C:19]1[C:14]([C:7]2[CH:8]=[CH:9][C:4]([C:1]([OH:3])=[O:2])=[CH:5][CH:6]=2)=[N:15][CH:16]=[CH:17][CH:18]=1

Participants

3

Reactant 2

HCID 169882,3-DichloropyridineHCID 3121834-Carboxyphenylboronic Acid

Product 1

HCID 221704544-(3-Chloropyridin-2-yl)benzoic acid

Procedure

The title compound may be prepared from 4-carboxybenzeneboronic acid and 2,3-dichloropyridine using the procedure outlined in Description 29 (D29), for the synthesis of 4-(6-methyl-2-pyridyl)-benzoic acid.

Sources & evidence

ORD record
ord-a5a051a72bbb47daad59ac260d0a0e72
Source dataset
uspto-grants-2009_05
Patent number
US07538121B2

Reaction notes

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