7-Aminoquinoline → 3-Methyl-N-quinolin-7-yl-1,1'biphenyl-4-carboxamide

Participants

Reaction Steps

Using the procedure outlined in Example 56, the title compound was prepared from 7-aminoquinoline (D55) (31, 0.22 mmol) and 3-methyl-1,1′-biphenyl-4-carboxylic acid (D58) (55 mg, 0.26 mmol) as an off-white solid. 1H NMR (400 MHz, CDCl3) δ (ppm): 8.91(dd, 1H), 8.14 (m, 3H), 7.86 (d, 1H), 7.78 (br, 1H), 7.66 (d, 1H), 7.62 (d, 2H), 7.53 (m, 2H), 7.48 (t, 2H), 7.40 (t, 1H), 7.36 (dd, 1H), 2.63 (s, 3H).

Provenance & Evidence