2-Methylquinolin-7-amine → HCID 57682716, compound

HRID 494252Notes

Reaction equation

HRID 494252 reaction equation
[NH2:1][C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[CH:7][C:8]([CH3:12])=[N:9]2)=[CH:4][CH:3]=1.[CH3:13][C:14]1[N:19]=[C:18]([C:20]2[CH:28]=[CH:27][C:23]([C:24](O)=[O:25])=[CH:22][CH:21]=2)[CH:17]=[CH:16][CH:15]=1>>[CH3:12][C:8]1[CH:7]=[CH:6][C:5]2[C:10](=[CH:11][C:2]([NH:1][C:24](=[O:25])[C:23]3[CH:27]=[CH:28][C:20]([C:18]4[CH:17]=[CH:16][CH:15]=[C:14]([CH3:13])[N:19]=4)=[CH:21][CH:22]=3)=[CH:3][CH:4]=2)[N:9]=1

Participants

3

Reactant 2

HCID 4596552-Methylquinolin-7-amineHCID 534263364-(6-Methylpyridin-2-yl)benzoic acid

Product 1

HCID 57682716HCID 57682716, compound

Procedure

Using the procedure outlined in Example 56, the title compound was prepared from 7-amino-2-methylquinoline (D66) (33 mg, 0.21 mmol) and 4-(6-methyl-2-pyridyl)benzoic acid (D29) (47 mg, 0.25 mmol) as an off-white solid. MS (ES): MH+ 354, M-H+ 352.

Sources & evidence

ORD record
ord-2c8690203ecb4ecfbc77ecef881fce23
Source dataset
uspto-grants-2009_05
Patent number
US07538121B2

Reaction notes

Loading…