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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 494279Generated: October 25, 2026

7-Aminoquinoline → HCID 57682719, compound

https://huagongshe.com/reaction/494279

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-AminoquinolineHCID 11377—
Reactant6-(4-Fluorophenyl)-2-(methoxymethyl)nicotinic acidHCID 69038801—
ProductHCID 57682719HCID 57682719—

Reaction Steps

Using the procedure outlined in Example 56, the title compound was prepared from 7-aminoquinoline (D55) (11 mg, 0.076 mmol) and 6-(4-fluorophenyl)-2-(methoxymethyl)-nicotinic acid (D86) (19 mg, 0.073 mmol) as an orange solid. 1H NMR (250 MHz, CDCl3) δ (ppm): 10.40 (br.s, 1H), 8.92 (dd, 1H), 8.41 (d, 1H), 8.29 (d, 1H), 8.05-8.20 (m, 4H), 7.85 (m, 2H), 7.36 (dd, 1H), 7.20 (t, 2H), 4.91 (s, 2H), 3.68 (s, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07538121B2
Source datasetuspto-grants-2009_05
ORD IDord-9f88439c88b44c448d6427f0fe087820
Source noteuspto-grants-2009_05