HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Aminoquinoline → 6-(3-Fluorophenyl)-2-methyl-N-quinolin-7-yl-nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Aminoquinoline | HCID 11377 | — |
| Reactant | 2-Methyl-6-(3-fluorophenyl)-nicotinic acid | HCID 69039601 | — |
| Product | 6-(3-Fluorophenyl)-2-methyl-N-quinolin-7-yl-nicotinamide | HCID 57682755 | — |
Reaction Steps
Using the procedure outlined in Example 56, the title compound was prepared from 7-aminoquinoline (D55) (28 mg, 0.20 mmol) and 6-(3-fluorophenyl)-2-methyl-nicotinic acid (D25) (50 mg, 0.33 mmol), as an off-white solid. MS(ES): MH+ 358, M-H+ 356.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07538121B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-865620f9b7e74b34b139e89bb8929b7d |
| Source note | uspto-grants-2009_05 |