反应详情

Using the procedure outlined in Example 56, the title compound was prepared from 7-amino-4-methyl-1-H-quinolin-2-one (50 mg, 0.29 mmol) and 4-biphenylcarboxylic acid (68 mg, 0.34 mmol) as a cream solid. 1H NMR (250 MHz, DMSO) δ (ppm): 11.60 (br, 1H), 10.55 (br, 1H), 8.09 (d, 2H), 8.02 (s, 1H), 7.86 (d, 2H), 7.77 (d, 2H), 7.69 (d, 1H), 7.55 (dd, 1H), 7.52 (t, 2H), 7.43 (t, 1H), 6.29 (s, 1H), 2.41 (s, 3H).