1,5-Naphthalenedisulfonic acid → HCID 87591570, compound

Participants

Reaction Steps

To a stirred solution of Example 42 (700 mg, 2.18 mmol) in acetone (10 ml) was added a solution of naphthalene-1,5-disulfonic acid (860 g, 2.46 mmol) in acetone (10 ml). The solution was stirred at room temperature for 30 min to give a white precipitate. The precipitate was collected by filtration and dried under vacuum to give 1.2 g of the product as a white solid; 1H NMR (D2O, 300 MHz) δ 1.25-1.41 (m, 2H), 1.60-1.70 (m, 2H), 1.88-2.01 (m, 1H), 2.24-2.65 (m, 3H), 3.40-4.06 (m, 6H), 4.21 (d, J=7.5 Hz, 2H), 4.91 (d, J=9.3 Hz, rotomer, 0.9H), 5.10 (d, J=9.1 Hz, rotomer, 0.1H), 5.32-5.49 (m, 1H), 7.67 (t, J=8.7 Hz, 2H), 8.14 (d, J=7.2 Hz, 2H), 8.41 (s, 1H), 8.77 (d, J=9.0 Hz, 2H), 9.12 (s, 1H).

Provenance & Evidence