Trifluoroacetic acid → HCID 11677427, compound

Participants

Reaction Steps

270 mg of tert-butyl 2-{(1S,3R)-3-[5-ethyl-2-(4-trifluoromethylphenyl)oxazol-4-ylmethoxymethyl]cyclohexylmethoxy}-2-methylpropionate are dissolved in 5 ml of dichloromethane and 2.5 ml of trifluoroacetic acid and stirred overnight. The solution is then completely evaporated, and the residue is purified by preparative HPLC, resulting in 127 mg of 2-{(1S,3R)-3-[5-ethyl-2-(4-trifluoromethylphenyl)oxazol-4-ylmethoxymethyl]cyclohexylmethoxy}-2-methylpropionic acid as yellow oil.

Provenance & Evidence