HCID 68871629, compound → HCID 135477805, compound

HRID 494463Notes

Reaction equation

[NH2:1][S:2]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[NH:11][C:12]([C:14]1[C:23](=[O:24])[C:22]([CH2:30][CH2:31][CH:32]([CH3:34])[CH3:33])([CH2:25][CH2:26][CH:27]([CH3:29])[CH3:28])[C:21]2[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=2)[C:15]=1[OH:35])=O)(=[O:4])=[O:3].NS(C1C=CC=CC=1NC(C1C(=O)C(CCCC)(CCCC)C2C(=CC=CC=2)C=1O)=O)(=O)=O>>[O:3]=[S:2]1(=[O:4])[C:5]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[NH:11][C:12]([C:14]2[C:23](=[O:24])[C:22]([CH2:25][CH2:26][CH:27]([CH3:29])[CH3:28])([CH2:30][CH2:31][CH:32]([CH3:33])[CH3:34])[C:21]3[C:16]([C:15]=2[OH:35])=[CH:17][CH:18]=[CH:19][CH:20]=3)=[N:1]1

Participants

Reactant 2

HCID 68871629HCID 68871629, compound

HCID 68872527HCID 68872527, compound

Product 1

HCID 135477805HCID 135477805, compound

Procedure

The title compound was prepared according to the procedure of Example 4H, substituting the product of Example 6G for the product of Example 4G. 1H NMR (300 MHz, CDCl3): δ 16.69 (d, J=12.13 Hz, 1 H), 14.39, 14.25 (s, 1 H), 8.28 (d, J=8.09 Hz, 1 H), 7.99 (d, J=8.09 Hz, 1 H), 7.67 (m, 2 H), 7.48 (q, J=7.72 Hz, 2 H), 7.31 (m, 2 H), 2.29 (m, 2 H), 1.93 (m, 2 H), 1.32 (m, 2 H), 0.82 (m, 14 H), 0.44 (m, 2 H).

Sources & evidence

ORD record: ord-c2992e76023b4cdcb837f50bc550532d
Source dataset: uspto-grants-2009_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07538105B2

Reaction notes

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