HRID494464

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCCC1(CCC)C(=O)C(C2=NS(=O)(=O)c3cc(OCc4ccccc4)ccc3N2)=C(O)c2ccccc21

HCID136375600

未命名化合物

结构：CC(C)CCC1(CCC(C)C)C(=O)C(C2=NS(=O)(=O)c3cc(OCc4ccccc4)ccc3N2)=C(O)c2ccccc21

HCID136375601

未命名化合物

PRODUCTS

生成物

结构：CC(C)CCC1(CCC(C)C)C(=O)C(C2=NS(=O)(=O)c3cc(O)ccc3N2)=C(O)c2ccccc21

HCID135495193

未命名化合物

PROCEDURE

实验过程

The title compound was prepared by the procedure of Example 2G, substituting the product of Example 7B for the product of Example 2F. 1H NMR (300 MHz, DMSO-d6): δ 13.69 (s, 1 H), 10.42 (s, 1 H), 8.17 (d, J=7.72 Hz, 1 H), 7.77 (m, 1 H), 7.56 (m, 3 H), 7.19 (m, 2 H), 2.12 (m, 4 H), 1.29 (m, 2 H), 0.75 (m, 14 H), 0.38 (m, 2 H).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-ed1b0f6985ba425b8532905307b7d1d0
来源数据集: uspto-grants-2009_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07538105B2
来源说明: uspto-grants-2009_05

反应 SMILES

C([O:8][C:9]1[CH:42]=[CH:41][C:12]2[NH:13][C:14]([C:19]3[C:20](=[O:40])[C:21]([CH2:35][CH2:36][CH:37]([CH3:39])[CH3:38])([CH2:30][CH2:31][CH:32]([CH3:34])[CH3:33])[C:22]4[C:27]([C:28]=3[OH:29])=[CH:26][CH:25]=[CH:24][CH:23]=4)=[N:15][S:16](=[O:18])(=[O:17])[C:11]=2[CH:10]=1)C1C=CC=CC=1.C(OC1C=CC2NC(C3C(=O)C(CCC)(CCC)C4C(C=3O)=CC=CC=4)=NS(=O)(=O)C=2C=1)C1C=CC=CC=1>>[OH:29][C:28]1[C:27]2[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=2)[C:21]([CH2:35][CH2:36][CH:37]([CH3:39])[CH3:38])([CH2:30][CH2:31][CH:32]([CH3:34])[CH3:33])[C:20](=[O:40])[C:19]=1[C:14]1[NH:13][C:12]2[CH:41]=[CH:42][C:9]([OH:8])=[CH:10][C:11]=2[S:16](=[O:17])(=[O:18])[N:15]=1