HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminobenzenesulfonamide → 3-(1,1-Dioxido-4h-1,2,4-benzothiadiazin-3-yl)-6-fluoro-4-hydroxy-1,1-dipropylnaphthalen-2(1h)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminobenzenesulfonamide | HCID 72894 | — |
| Reactant | 2-[bis(methylsulfanyl)methylene]-4,4-dibutyl-1,3(2H,4H)-naphthalenedione | HCID 11211104 | — |
| Reactant | 2-[Bis(methylthio)methylene]-7-fluoro-4,4-dipropylnaphthalene-1,3(2h,4h)-dione | HCID 11485414 | — |
| Reactant | 2-Amino-5-(benzyloxy)benzenesulfonamide | HCID 67063986 | — |
| Product | 3-(1,1-Dioxido-4h-1,2,4-benzothiadiazin-3-yl)-6-fluoro-4-hydroxy-1,1-dipropylnaphthalen-2(1h)-one | HCID 136337547 | — |
Reaction Steps
The title compound was prepared according to the procedure of Example 5D, substituting the compound of Example 14H for the compound of Example 5C, and also substituting 2-aminobenzenesulfonamide for the compound of Example 2D. 1H NMR (300 MHz, DMSO-d6): δ 0.58 (m, 2 H) 0.67 (m, 6 H) 0.93 (m, 2 H) 2.01 (m, 2 H) 2.17 (m, 2 H) 7.72 (m, 7 H) 13.48 (s, 1-H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07538105B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-e193b61643e940a58bf1f9e4fa7d4f8b |
| Source note | uspto-grants-2009_05 |