Methyl 2-phenyl-2-propylpentanoate → 2-(4-Fluorophenyl)-2,5-dimethylhexanoic acid

HRID 494498Notes

Reaction equation

HRID 494498 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([CH3:18])([CH2:13][CH2:14][CH:15]([CH3:17])[CH3:16])[C:9]([O:11]C)=[O:10])=[CH:4][CH:3]=1.C1(C(CCC)(CCC)C(OC)=O)C=CC=CC=1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]([CH3:18])([CH2:13][CH2:14][CH:15]([CH3:16])[CH3:17])[C:9]([OH:11])=[O:10])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 11658708Methyl 2-phenyl-2-propylpentanoateHCID 68872679Methyl 2-(4-fluorophenyl)-2,5-dimethylhexanoate

Product 1

HCID 688699802-(4-Fluorophenyl)-2,5-dimethylhexanoic acid

Procedure

The title compound was prepared according to the procedure of Example 1C, substituting the compound of Example 22B for the compound of Example 1B. 1H NMR (300 MHz, CDCl3): δ 0.86 (t, J=6.43 Hz, 6 H) 1.05 (m, 2 H) 1.51 (m, 4 H) 1.96 (m, 2 H) 7.02 (m, 2 H) 7.34 (m, 2 H).

Sources & evidence

ORD record
ord-2a168cabdfa8437baeffe0a8050076b3
Source dataset
uspto-grants-2009_05
Patent number
US07538105B2

Reaction notes

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