Hydrochloric Acid → HCID 135869475, compound

Participants

Reaction Steps

A solution of Example 40G (3.24, 6.00 mmol) in 4M hydrochloric acid in 1,4-dioxane (10 mL) was stirred at 25° C. for 1 hour. The solution was concentrated in vacuo and the residue was triturated in diethyl ether to give the title compound (2.86 g, 99%). 1H NMR (300 MHz, DMSO-d6): δ ppm 0.42 (m, 1H) 0.74 (m, 7H) 1.32 (m, 1H) 1.58 (m, 3H) 2.15 (m, 2H) 7.07 (m, 2H) 7.51 (m, 2H) 7.77 (m, 2H) 8.16 (m, 1H) 13.57 (m, 1H). MS (ESI−) m/z 438 (M−H)−.

Provenance & Evidence