Pentanoic Acid → HCID 59773977, compound

Participants

Reaction Steps

n-Pentanoic acid (1.02 g, 10 mmol) was added slowly dropwise to chlorosulfonyl isocyanate (1.42 g, 10 mmol), with ice/water bath cooling as required to maintain gentle gas evolution. After the addition was complete, the residue was taken up in benzene (10 mL) and the mixture concentrated in vacuo to provide the title compound(2.0 g, quantitative) as a crystalline, hygroscopic solid.

Provenance & Evidence