HCID 68871456, compound → HCID 68870978, compound

HRID 494653Notes

Reaction equation

HRID 494653 reaction equation
[OH:1][CH2:2][CH2:3][N:4]([CH3:24])[C:5]([C:7]1([CH2:19][CH2:20][CH:21]([CH3:23])[CH3:22])[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[CH2:10][CH:9]=[C:8]1[O:17][CH3:18])=[O:6].C[O:26][C:27]1[C@](C(N2CCC[C@@H]2CO)=O)(CCC(C)C)C2C(C[CH:36]=1)=CC=CC=2>>[C:27]([O:1][CH2:2][CH2:3][N:4]([C:5]([C:7]1([CH2:19][CH2:20][CH:21]([CH3:22])[CH3:23])[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[CH2:10][CH:9]=[C:8]1[O:17][CH3:18])=[O:6])[CH3:24])(=[O:26])[CH3:36]

Participants

3

Reactant 2

HCID 68871456HCID 68871456, compoundHCID 68874183HCID 68874183, compound

Product 1

HCID 68870978HCID 68870978, compound

Procedure

The title compound was prepared using the procedure described for Example 171C, substituting the product from Example 176B for the product from Example 171B. The title compound was purified by column chromatography on silica gel using a solvent gradient of 35-65% ethyl acetate in hexane, and was obtained as a colorless solid.

Workup

  1. customThe title compound was purified by column chromatography on silica gel using a solvent gradient of 35-65% ethyl acetate in hexane
  2. customwas obtained as a colorless solid

Sources & evidence

ORD record
ord-a983e29b6d1046d6ac018a8e7c4190d3
Source dataset
uspto-grants-2009_05
Patent number
US07538105B2

Reaction notes

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