HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → 4-[2-(2-Pyrrolidin-1-yl-ethyl)-benzofuran-5-yl]-benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | 2-[5-(4-cyanophenyl)-1-benzofuran-2-yl]ethyl Methanesulfonate | HCID 11393678 | — |
| Product | 4-[2-(2-Pyrrolidin-1-yl-ethyl)-benzofuran-5-yl]-benzonitrile | HCID 10087134 | — |
Reaction Steps
The product from Example 1C and pyrrolidine were processed as described in Example 1D to provide the titled compound. 1H NMR (300 MHz, CD3OD) δ 7.7 (m, 5H), 7.50 (d, J=8.7 Hz, 1H), 7.42 (dd, J=8.7, 1.5 Hz, 1H), 6.51 (s, 1H), 3.1 (m 2H), 2.95 (m, 2H), 2.65 (m, 4H), 1.9 (m, 4H); MS (DCI) m/z 317 (M+H)+;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07538138B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-e64134ca7c5a41ba9c755f80f0b8f08a |
| Source note | uspto-grants-2009_05 |