Imidazole → HCID 10086941, compound

HRID 494767Notes

Reaction equation

HRID 494767 reaction equation
CS(O[CH2:6][CH2:7][C:8]1[O:9][C:10]2[CH:16]=[CH:15][C:14]([C:17]3[CH:22]=[CH:21][C:20]([C:23]#[N:24])=[CH:19][CH:18]=3)=[CH:13][C:11]=2[CH:12]=1)(=O)=O.[NH:25]1[CH:29]=[CH:28][N:27]=[CH:26]1>>[N:25]1([CH2:6][CH2:7][C:8]2[O:9][C:10]3[CH:16]=[CH:15][C:14]([C:17]4[CH:22]=[CH:21][C:20]([C:23]#[N:24])=[CH:19][CH:18]=4)=[CH:13][C:11]=3[CH:12]=2)[CH:29]=[CH:28][N:27]=[CH:26]1

Participants

3

Reactant 2

HCID 795ImidazoleHCID 113936782-[5-(4-cyanophenyl)-1-benzofuran-2-yl]ethyl Methanesulfonate

Product 1

HCID 10086941HCID 10086941, compound

Procedure

The product from Example 1C and imidazole were processed as described in Example 1D to provide the titled compound. 1H NMR (300 MHz, CD3OD) δ 8.88 (s, 1H), 7.88 (m, 1H), 7.80 (m, 5H), 7.60 (m, 4H), 6.75 (s, 1H), 4.7 (t, J=6.3 Hz, 2H), 3.5 (t, J=6.3 Hz, 2H); MS (DCI) m/z 314 (M+H)+;

Sources & evidence

ORD record
ord-64a987be2eb94908bd9d0f7fa7463200
Source dataset
uspto-grants-2009_05
Patent number
US07538138B2

Reaction notes

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