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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 494770Generated: October 30, 2026

1H-Azepine → 4-[2-(2-Azepan-1-yl-ethyl)-benzofuran-5-yl]-benzonitrile

https://huagongshe.com/reaction/494770

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-AzepineHCID 6451476—
Reactant2-[5-(4-cyanophenyl)-1-benzofuran-2-yl]ethyl MethanesulfonateHCID 11393678—
Product4-[2-(2-Azepan-1-yl-ethyl)-benzofuran-5-yl]-benzonitrileHCID 9902719—

Reaction Steps

The product from Example 1C and azepine were processed as described in Example 1D to provide the titled compound. MS (DCI) m/z 345 (M+H)+;

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07538138B2
Source datasetuspto-grants-2009_05
ORD IDord-94403fe426c94406ac67b01707fe6ae8
Source noteuspto-grants-2009_05