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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 494782Generated: October 25, 2026

Diethylamine → N,N-diethyl-N-(2-{5-[4-(4-morpholinylcarbonyl)phenyl]-1-benzofuran-2-yl}ethyl)amine

https://huagongshe.com/reaction/494782

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethylamineHCID 8021—
Reactant2-{5-[4-(4-Morpholinylcarbonyl)phenyl]-1-benzofuran-2-yl}ethyl methanesulfonateHCID 22274531—
ProductN,N-diethyl-N-(2-{5-[4-(4-morpholinylcarbonyl)phenyl]-1-benzofuran-2-yl}ethyl)amineHCID 10201388—

Reaction Steps

The product from Example 23D and diethylamine were processed as described in Example 1D to provide the titled compound. 1H NMR (300 MHz, CD3OD) δ 7.82 (m, 1H), 7.74 (d, J=8.1, 2H), 7.54 (m, 2H), 7.51 (d, J=8.1 Hz, 2H), 6.80 (s, 1H), 3.32-3.8 (m, 16H), 1.38 (t, J=7.5 Hz, 6H); MS (DCI) m/z 407 (M+H)+;

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07538138B2
Source datasetuspto-grants-2009_05
ORD IDord-daba43c75e69493992731792c74b7554
Source noteuspto-grants-2009_05