Iodine → (2-Fluorophenyl)(4-hydroxy-3-iodophenyl)methanone

HRID 494823Notes

Reaction equation

[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]([C:10]1[CH:15]=[CH:14][C:13]([OH:16])=[CH:12][CH:11]=1)=[O:9].[I-:17].[K+].II>>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]([C:10]1[CH:11]=[CH:12][C:13]([OH:16])=[C:14]([I:17])[CH:15]=1)=[O:9]

Participants

Reactant 3

HCID 807Iodine

HCID 4875Potassium Iodide

HCID 27832352-Fluoro-4'-hydroxybenzophenone

Product 1

HCID 11279298(2-Fluorophenyl)(4-hydroxy-3-iodophenyl)methanone

Procedure

(2-Fluorophenyl)(4-hydroxyphenyl)methanone, potassium iodide and iodine were processed as described in Example 68A to provide the title compound. MS (DCI) m/z 343 (M+H)+, 360 (M+NH4)+.

Sources & evidence

ORD record: ord-bbd259e5117b419bb4ad42664ecb6c06
Source dataset: uspto-grants-2009_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07538138B2

Reaction notes

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