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HRID494836

反应详情

EQUATION

反应方程式

HRID 494836 的结构方程式

REACTANTS

反应物

2
结构：CON(C)C(=O)c1ccc2oc(CCN3CCC[C@H]3C)cc2c1
HCID11438480

未命名化合物

结构：CN(C)c1ccc([Mg]Br)cc1
HCID178482849

未命名化合物

PRODUCTS

生成物

1
结构：C[C@@H]1CCCN1CCc1cc2cc(C(=O)c3ccc(N(C)C)cc3)ccc2o1
HCID10110088

[4-(Dimethylamino)phenyl][2-[2-[(2R)-2-methyl-1-pyrrolidinyl]ethyl]-5-benzofuranyl]methanone

C24H28N2O2

PROCEDURE

实验过程

The product from Example 71E and 4-(dimethylamino)phenylmagnesium bromide were processed as described in Example 71F to provide the title compound. 1HNMR (300 MHz, CD3OD) δ 1.44 (d, 3H), 1.73 (m, 1H), 1.80 (m, 2H), 2.15 (m, 2H), 2.35 (m, 1H), 3.18 (s, 6H), 3.50 (m, 2H), 3.55 (m, 1H), 3.80 (m, 2H), 6.80 (dd, 2H), 6.85 (s, 1H), 7.56 (dd, 1H), 7.65 (dd, 1H), 7.75 (dd, 2H), 7.95 (d, 1H); MS (ESI) m/z 377 (M+H)+.