HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-methoxy-N-methyl-2-{2-[(2R)-2-methyl-1-pyrrolidinyl]ethyl}-1-benzofuran-5-carboxamide → HCID 10132440, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-methoxy-N-methyl-2-{2-[(2R)-2-methyl-1-pyrrolidinyl]ethyl}-1-benzofuran-5-carboxamide | HCID 11438480 | — |
| Reactant | HCID 178418370 | HCID 178418370 | — |
| Product | HCID 10132440 | HCID 10132440 | — |
Reaction Steps
The product from Example 71E and 4-methylphenylmagnesium bromide were processed as described in Example 71F to provide the title compound. 1HNMR (300 MHz, CD3OD) δ 1.48 (d, 3H), 1.75 (m, 1H), 2.1 (m, 2H), 2.38 (m, 1H), 2.45 (s, 3H), 3.30 (m, 4H), 3.57 (m, 1H), 3.80 (m, 2H), 6.85 (s, 1H), 7.38 (dd, 2H), 7.60 (dd, 1H), 7.70 (dd, 2H), 7.75 (dd, 1H), 8.0 (d, 1H); MS (ESI) m/z 348 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07538138B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-08b4658dd61241c49b12de9b22c7f1a8 |
| Source note | uspto-grants-2009_05 |