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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 494839Generated: October 28, 2026

N-methoxy-N-methyl-2-{2-[(2R)-2-methyl-1-pyrrolidinyl]ethyl}-1-benzofuran-5-carboxamide → HCID 10270078, compound

https://huagongshe.com/reaction/494839

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-methoxy-N-methyl-2-{2-[(2R)-2-methyl-1-pyrrolidinyl]ethyl}-1-benzofuran-5-carboxamideHCID 11438480—
ReactantHCID 178489560HCID 178489560—
ProductHCID 10270078HCID 10270078—

Reaction Steps

The product from Example 71E and 2-methoxyphenylmagnesium bromide were processed as described in Example 71F to provide the title compound. 1HNMR (300 MHz, CD3OD) δ 1.42 (d, 3H), 1.72 (m, 1H), 2.10 (m, 2H), 2.35 (m, 1H), 3.30 (m, 4H), 3.55 (m, 1H), 3.70 (s 3H), 3.80 (m, 2H), 6.80 (s, 1H), 7.1 (m, 2H), 7.30 (dd, 1H), 7.53 (m, 2H), 7.75 (dd, 1H), 7.95 (d, 1H); MS (ESI) m/z 364 (M+14H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07538138B2
Source datasetuspto-grants-2009_05
ORD IDord-b6089d0fc90c421ba5af6142fd0318a5
Source noteuspto-grants-2009_05