Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 494840Generated: October 30, 2026

N-methoxy-N-methyl-2-{2-[(2R)-2-methyl-1-pyrrolidinyl]ethyl}-1-benzofuran-5-carboxamide → HCID 10155614, compound

https://huagongshe.com/reaction/494840

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-methoxy-N-methyl-2-{2-[(2R)-2-methyl-1-pyrrolidinyl]ethyl}-1-benzofuran-5-carboxamideHCID 11438480—
ReactantHCID 178490745HCID 178490745—
ProductHCID 10155614HCID 10155614—

Reaction Steps

The product from Example 71E and 3-methoxyphenylmagnesium bromide were processed as described in Example 71F to provide the title compound. 1HNMR (300 MHz, CD3OD) δ 1.42 (d, 3H), 1.72 (m, 1H), 2.10 (m, 2H), 2.35 (m, 1H), 3.30 (m, 4H), 3.55 (m, 1H), 3.80 (m, 2H), 3.83 (s, 3H), 6.83 (s, 1H), 7.2 (m, 1H), 7.30 (m, 2H), 7.45 (m, 1H), 7.60 (m, 2H), 7.80 (dd, 1H), 8.02 (d, 1H); MS (ESI) m/z 364 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07538138B2
Source datasetuspto-grants-2009_05
ORD IDord-eecc89769a4f40b5975949a63676ea9e
Source noteuspto-grants-2009_05