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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 494872Generated: October 29, 2026

HCID 11234748, compound → HCID 10133949, compound

https://huagongshe.com/reaction/494872

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 11234748HCID 11234748—
ReactantHCID 178418630HCID 178418630—
ProductHCID 10133949HCID 1013394948%

Reaction Steps

The product from Example 145 and cyclopropylmagnesium bromide were processed as described in Example 146 to provide the title compound (48% yield). MS (ESI APCI) m/z 374 (M+H)+; 1HNMR (300 MHz, CD3OD) δ 1.08-1.22 (m, 7H), 1.39-1.53 (m, 1H), 1.73-1.86 (m, 2H), 1.95-2.08 (m, 1H), 2.23-2.35 (m, 1H), 2.41-2.60 (m, 2H), 2.87-3.15 (m, 3H), 3.19-3.35 (m, 2H), 6.63 (s, 1H), 7.48-7.55 (m, 2H), 7.60 (dd, 1H), 7.78-7.81 (m, 1H), 7.89 (ddd, 1H), 8.02 (ddd, 1H), 8.25 (dd, 1H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07538138B2
Source datasetuspto-grants-2009_05
ORD IDord-bc22b05fc424400793b0641f9a2dfc7b
Source noteuspto-grants-2009_05