HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 11234748, compound → HCID 10133949, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 11234748 | HCID 11234748 | — |
| Reactant | HCID 178418630 | HCID 178418630 | — |
| Product | HCID 10133949 | HCID 10133949 | 48% |
Reaction Steps
The product from Example 145 and cyclopropylmagnesium bromide were processed as described in Example 146 to provide the title compound (48% yield). MS (ESI APCI) m/z 374 (M+H)+; 1HNMR (300 MHz, CD3OD) δ 1.08-1.22 (m, 7H), 1.39-1.53 (m, 1H), 1.73-1.86 (m, 2H), 1.95-2.08 (m, 1H), 2.23-2.35 (m, 1H), 2.41-2.60 (m, 2H), 2.87-3.15 (m, 3H), 3.19-3.35 (m, 2H), 6.63 (s, 1H), 7.48-7.55 (m, 2H), 7.60 (dd, 1H), 7.78-7.81 (m, 1H), 7.89 (ddd, 1H), 8.02 (ddd, 1H), 8.25 (dd, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07538138B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-bc22b05fc424400793b0641f9a2dfc7b |
| Source note | uspto-grants-2009_05 |