4-Pentyn-1-ol → 3-(5-Bromo-1-benzofuran-2-yl)propan-1-ol

HRID 494891Notes

Reaction equation

HRID 494891 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[C:4](I)[CH:3]=1.[CH2:10]([OH:15])[CH2:11][CH2:12][C:13]#[CH:14]>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]2[O:8][C:13]([CH2:12][CH2:11][CH2:10][OH:15])=[CH:14][C:4]=2[CH:3]=1

Participants

3

Reactant 2

HCID 793464-Pentyn-1-olHCID 109245324-Bromo-2-iodophenol

Product 1

HCID 222746933-(5-Bromo-1-benzofuran-2-yl)propan-1-ol

Procedure

The product from Example 112A and 4-pentyn-1-ol is processed as described in Example 112B to provide the title compound.

Sources & evidence

ORD record
ord-62c91d6af7704964ad57b42043df5a5f
Source dataset
uspto-grants-2009_05
Patent number
US07538138B2

Reaction notes

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