HCID 22326467, compound → [3-(Furan-2-yl)phenyl]acetic acid

Participants

Reaction Steps

To a solution of the methyl 3-(2-furanyl)phenylacetate from step (b) in 5 ml of methanol was added 10 ml of 1N NaOH aqueous solution, the resulting solution was stirred overnight before diluting with 40 of ml 1N NaOH aqueous solution and washing with 2×30 ml CH2Cl2. The aqueous solution was then acidified with 2N HCl, and extracted with 3×30 ml of CH2Cl2. The organic extracts were combined and were dried with MgSO4, filtered, and evaporated to give 0.32 g of the product as a golden-colored solid.

Provenance & Evidence