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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 495577Generated: October 30, 2026

(2-Amino-5-bromophenyl)(pyridin-4-yl)methanone → N-[4-Bromo-2-(pyridine-4-carbonyl)-phenyl]-4-isopropoxy-benzenesulfonamide

https://huagongshe.com/reaction/495577

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Amino-5-bromophenyl)(pyridin-4-yl)methanoneHCID 13549724—
Reactant4-(Propan-2-yloxy)benzene-1-sulfonyl chlorideHCID 22327297—
ProductN-[4-Bromo-2-(pyridine-4-carbonyl)-phenyl]-4-isopropoxy-benzenesulfonamideHCID 11754687—

Reaction Steps

The title compound was prepared according to the general procedure for the synthesis of N-Aryl-benzenesulfonamides previously described using 138 mg of (2-Amino-5-bromo-phenyl)-pyridin-4-yl-methanone and 117 mg of 4-Isopropoxy-benzenesulfonyl chloride. 1H-NMR (400 MHz, CDCl3): δ 1.31 (d, 6H, J=6 Hz), 4.49 (q, 1H, J=6.0 Hz), 6.73 (d, 2H, J=6.8 Hz), 7.39 (m, 3H), 7.63-7.70 (m, 4H), 8.82 (d, 2H, J=6.0 Hz), 9.99 (s, 1H). MS: m/z 476.0 (M++1)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06939885B2
Source datasetuspto-grants-2005_09
ORD IDord-8f2cef6216104bcf83f53e715c66f1ec
Source noteuspto-grants-2005_09