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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 495581Generated: October 31, 2026

4-t-Butylbenzenesulfonyl chloride → HCID 22327325, compound

https://huagongshe.com/reaction/495581

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-t-Butylbenzenesulfonyl chlorideHCID 139882—
ReactantHCID 22327294HCID 22327294—
ProductHCID 22327325HCID 22327325—

Reaction Steps

The title compound was prepared according to the general procedure for the synthesis of N-Aryl-benzenesulfonamides previously described using (2-Amino-5-chloro-phenyl)-(6-chloro-pyridin-3-yl)-methanone and 4-tert-butyl-benzenesulfonyl chloride and purified by HPLC. 1H NMR: δ 1.21 (s, 9H), 7.30 (d, J=2.4 Hz, 1H), 7.33 (d, J=6.6 Hz, 2H), 7.43 (d, J=8.0 Hz, 1H), 7.52 & 7.55 (dd, J=8.8 Hz, 2.8 Hz, 1H), 7.60 (d, J=7.0 Hz, 1H), 7.79 (m, 3H), 8.27 (d, J=2.0 Hz, 1H), 9.73 (s, 1H). MS: M/z 463.0 (M++1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06939885B2
Source datasetuspto-grants-2005_09
ORD IDord-586e9de9fa2240a0be26e44d3352fa6e
Source noteuspto-grants-2005_09