HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methanesulfonylbenzene-1-sulfonyl chloride → N-[4-Chloro-2-(2-methyl-pyridine-4-carbonyl)-phenyl]-4-methanesulfonyl-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methanesulfonylbenzene-1-sulfonyl chloride | HCID 2735182 | — |
| Reactant | (2-Amino-5-chloro-phenyl)-(2-methyl-pyridin-4-yl)-methanone | HCID 22327293 | — |
| Product | N-[4-Chloro-2-(2-methyl-pyridine-4-carbonyl)-phenyl]-4-methanesulfonyl-benzenesulfonamide | HCID 10253911 | — |
Reaction Steps
The title compound was prepared according to the general procedure for the synthesis of N-Aryl-benzenesulfonamides previously described using (2-Amino-5-chloro-phenyl)-(2-methyl-pyridin-4-yl)-methanone and 4-methanesulfonyl-benzenesulfonyl chloride and purified by HPLC. 1H NMR (CDCl3) δ 10.38 (s, 1H) 8.64 (s 1H) 7.95 (s, 4H) 7.72 (s, 1H) 7.51 (s, 1H) 7.31 (s, 1H) 7.11 (s, 1H) 6.99 (s, 1H) 3.04 (s, 3H) 2.64 (s, 3H). MS: (ES) m/z=464.9 (M++1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06939885B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-a3f3b371d5cd45e9a05da03b2b67915f |
| Source note | uspto-grants-2005_09 |