HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-[4-(4-(5-Nitroindol-3-yl)butyl)piperazino]-1,4-benzodioxane → 6-[4-(4-(5-Aminoindol-3-yl)butyl)piperazino]-1,4-benzodioxane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-[4-(4-(5-Nitroindol-3-yl)butyl)piperazino]-1,4-benzodioxane | HCID 19797324 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 6-[4-(4-(5-Aminoindol-3-yl)butyl)piperazino]-1,4-benzodioxane | HCID 19797340 | — |
Reaction Steps
A suspension of 3.8 g of 6-[4-(4-(5-nitroindol-3-yl)butyl)piperazino]-1,4-benzodioxane in 45 ml of methanol is hydrogenated with stirring on 0.1% Pd-C at 20° and 1 bar until absorption of H2 is complete. The mixture is poured into ice-water, worked up in the conventional manner and gives 6-[4-(4-(5-aminoindol-3-yl)butyl)piperazino]-1,4-benzodioxane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05242925 |
| Source dataset | uspto-grants-1993_09 |
| ORD ID | ord-e38ff13a85fc45659c62ccbd6fef9407 |
| Source note | uspto-grants-1993_09 |