Sodium Hydroxide → 2-Vinyloxytetrahydropyran

HRID 496048Notes

Reaction equation

HRID 496048 reaction equation
Cl[CH2:2][CH2:3][O:4][CH:5]1[CH2:10][CH2:9][CH2:8][CH2:7][O:6]1.[OH-].[Na+].S([O-])([O-])(=O)=O.C([N+](CCCC)(CCCC)CCCC)CCC.C([N+](CCCC)(CCCC)CCCC)CCC>>[CH:3]([O:4][CH:5]1[CH2:10][CH2:9][CH2:8][CH2:7][O:6]1)=[CH2:2]

Participants

4

Reactant 3

HCID 14798Sodium HydroxideHCID 2549512-(2-Chloroethoxy)tetrahydro-2H-pyranHCID 11433187Bis(tetrabutylammonium) sulphate

Product 1

HCID 115283452-Vinyloxytetrahydropyran

Procedure

A mixture of 1.52 mol of 2-(2-chloroethoxy)-tetrahydro-2H-pyran, 93 g of sodium hydroxide reduced to a powder and 25 g of tetrabutylammonium monosulphate is stirred for 1 hour and then distilled at 50° C. and 20 torr. The distillate is then dried over sodium sulphate, allowing the expected product to be isolated.

Workup

  1. distillationdistilled at 50° C.
  2. dry with materialThe distillate is then dried over sodium sulphate
  3. customto be isolated

Sources & evidence

ORD record
ord-0ed939e309994ea1813b6a90603704db
Source dataset
uspto-grants-2005_09
Patent number
US06943184B2

Reaction notes

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