HCID 70143145, compound → HCID 17840539, compound

HRID 496075Notes

Reaction equation

HRID 496075 reaction equation
[CH3:1][N:2]([C:10]1(/[CH:13]=[CH:14]\[C:15]2[CH:16]=[N:17][CH:18]=[CH:19][CH:20]=2)[CH2:12][CH2:11]1)[C:3](=[O:9])[O:4][C:5]([CH3:8])([CH3:7])[CH3:6]>CO.[Pd]>[CH3:1][N:2]([C:10]1([CH2:13][CH2:14][C:15]2[CH:16]=[N:17][CH:18]=[CH:19][CH:20]=2)[CH2:12][CH2:11]1)[C:3](=[O:9])[O:4][C:5]([CH3:8])([CH3:6])[CH3:7]

Participants

4

Reactant 1

HCID 70143145HCID 70143145, compound

Product 1

HCID 17840539HCID 17840539, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

5.1 g of the product obtained in Step 1 dissolved in 120 ml of methanol are hydrogenated in the presence of 1 g of 10% palladium-on-carbon (20° C., 1 bar, 3 hours). The catalyst is filtered off and rinsed with methanol; concentrating to dryness and drying at 45° C. and 0.5 torr allows the desired product to be obtained.

Workup

  1. filtrationThe catalyst is filtered off
  2. washrinsed with methanol
  3. concentrationconcentrating to dryness
  4. customdrying at 45° C.
  5. customto be obtained

Sources & evidence

ORD record
ord-66674ca3d4fd4b8eb5749b467e4a9431
Source dataset
uspto-grants-2005_09
Patent number
US06943184B2

Reaction notes

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