HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18719787, compound → (2S)-3H-4-Azaspiro[bicyclo[2.2.2]octane-2,2-furo[2,3-B]pyridin]-5-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18719787 | HCID 18719787 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | (2S)-3H-4-Azaspiro[bicyclo[2.2.2]octane-2,2-furo[2,3-B]pyridin]-5-amine | HCID 18719785 | 92% |
Reaction Steps
The enantiomer (S)-(+)-5′nitrospiro[1-azabicyclo[2.2.2]octane-3,2′(3′H)-furo[2,3-b]pyridine] (6.85 g, 26.2 mmol) treated in the same way as described in example 8A in ammoniated methanol provided the title compound (5.55 g, 24 mmol, 92%): electrospray MS (m/z, relative intensity) 232 ([MH]+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06706878B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-a8f0585e6f614b12bf6128afa4dbc21e |
| Source note | uspto-grants-2004_03 |