HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexanecarboxaldehyde → 3-Cyclohexyl-7-(2',4'-dimethoxyphenyl)-1,2,3,4-tetrahydro-1,2,4-benzothiadiazine-1,1-dioxide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexanecarboxaldehyde | HCID 16275 | — |
| Reactant | 2,4-Dimethoxybenzeneboronic acid | HCID 2734341 | — |
| Reactant | 2-Amino-5-cyanobenzene-1-sulfonamide | HCID 22323994 | — |
| Product | 3-Cyclohexyl-7-(2',4'-dimethoxyphenyl)-1,2,3,4-tetrahydro-1,2,4-benzothiadiazine-1,1-dioxide | HCID 22324011 | — |
Reaction Steps
5-Iodo-2-aminobenzenesulfonamide (see compound 37) was transformed by Method H (using 2,4-dimethoxyphenylboronic acid) and Method G (using cyclohexanecarboxaldehyde). M.p. 208-213° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06943159B1 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-7e61584f73cd46e7b8b01026a9116a86 |
| Source note | uspto-grants-2005_09 |