HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexanecarboxaldehyde → 3-Cyclohexyl-7-(2'-(N,N-dimethylsulfamoyl)phenyl)-1,2,3,4-tetrahydro-1,2,4-benzothiadiazine-1,1-dioxide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexanecarboxaldehyde | HCID 16275 | — |
| Reactant | 2-(N,N-dimethylsulphamoyl)benzeneboronic acid | HCID 4197348 | — |
| Reactant | 2-Amino-5-cyanobenzene-1-sulfonamide | HCID 22323994 | — |
| Product | 3-Cyclohexyl-7-(2'-(N,N-dimethylsulfamoyl)phenyl)-1,2,3,4-tetrahydro-1,2,4-benzothiadiazine-1,1-dioxide | HCID 22324078 | — |
Reaction Steps
5-Iodo-2-aminobenzenesulfonamide (see compound 37) was transformed by Method H (using 2-(N,N-dimethylsulfamoyl)phenylboronic acid) and Method G (using cyclohexanecarboxaldehyde). M.p. 290-300° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06943159B1 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-a37db8faadfb4277bf3a3e9c601c1d2a |
| Source note | uspto-grants-2005_09 |