Cyclohexanecarboxaldehyde → 3-Cyclohexyl-5,7-dibromo-1,2,3,4-tetrahydro-1,2,4-benzothiadiazine-1,1-dioxide

HRID 496149Notes

Reaction equation

HRID 496149 reaction equation
[NH2:1][C:2]1[C:7]([Br:8])=[CH:6][C:5]([Br:9])=[CH:4][C:3]=1[S:10]([NH2:13])(=[O:12])=[O:11].[CH:14]1([CH:20]=O)[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1>>[CH:14]1([CH:20]2[NH:1][C:2]3[C:7]([Br:8])=[CH:6][C:5]([Br:9])=[CH:4][C:3]=3[S:10](=[O:12])(=[O:11])[NH:13]2)[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1

Participants

3

Reactant 2

HCID 16275CyclohexanecarboxaldehydeHCID 12013962-Amino-3,5-dibromobenzenesulfonamide2×

Product 1

HCID 223240673-Cyclohexyl-5,7-dibromo-1,2,3,4-tetrahydro-1,2,4-benzothiadiazine-1,1-dioxide

Procedure

2-Amino-3,5-dibromobenzenesulfonamide (see compound 125) was transformed by Method G (using cyclohexanecarboxaldehyde). M.p. 166-167° C.

Sources & evidence

ORD record
ord-28fbd32d3340473eadaa1d4923ea11dd
Source dataset
uspto-grants-2005_09
Patent number
US06943159B1

Reaction notes

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