3,4-Dichlorophenol → HCID 26192742, compound

HRID 496202Notes

Reaction equation

HRID 496202 reaction equation
[CH3:1][O:2][C:3](=[O:17])[C@@H:4]1[CH2:8][C@H:7]([OH:9])[CH2:6][N:5]1C(OC(C)(C)C)=O.[Cl:18][C:19]1[CH:20]=[C:21](O)[CH:22]=[CH:23][C:24]=1[Cl:25]>>[Cl:18][C:19]1[CH:20]=[C:21]([CH:22]=[CH:23][C:24]=1[Cl:25])[O:9][C@@H:7]1[CH2:6][NH:5][C@H:4]([C:3]([O:2][CH3:1])=[O:17])[CH2:8]1

Participants

3

Reactant 2

HCID 72583,4-DichlorophenolHCID 10752873N-Boc-cis-4-hydroxy-L-proline methyl ester

Product 1

HCID 26192742HCID 26192742, compound

Procedure

The compound was prepared by analogy with Example 217(ii) from N-Boc-cis-4-hydroxy-L-proline methylester and 3,4-dichlorophenol.

Sources & evidence

ORD record
ord-06dd3f254796403fa93ccc010f0675c3
Source dataset
uspto-grants-2005_09
Patent number
US06943188B2

Reaction notes

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